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mechanisms

Amide Hydrolysis

Amide Hydrolysis – Conversion of Amides To Carboxylic Acids In this post we discuss examples and mechanism of acidic hydrolysis of amides, as well as

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All About Enamines

Enamines – formation, properties, reactions, and mechanisms.  Enamines are formed from the reaction of a secondary amine with an aldehyde or ketone. Because they have

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Summary Sheet: Additions to Carbonyls

I put together this summary sheet for the reaction of nucleophiles with carbonyls (click for larger image, see link to downloadable PDF below). It summarizes the two key concepts that are important to understand for these reactions: the effect of electronic and steric factors on nucleophilic addition.

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