The Second-Most Important Mechanism In Carbonyl Chemistry – Carbonyl Elimination The reverse of nucleophilic addition to the C=O bond (giving a tetrahedral intermediate) is elimination
Read moreProton Transfer All acid-base reactions are technically proton transfers, where a bond to H+ breaks, and a bond to H+ forms. However, the term “proton
Read moreThe Simple Two-Step Pattern For Seven Key Reactions Of Aldehydes And Ketones “There are just so many reactions! I can’t remember all the mechanisms!!” – distressed
Read moreToday I’m delighted to announce a new book – Practice Organic Mechanisms, co-written with Dr. Michelle Sulikowski, Senior Lecturer of Organic Chemistry at Vanderbilt University. Practice Organic
Read moreHalogenation of Alkynes With Br2 and Cl2 Like alkenes, alkynes can undergo halogenation with Cl2, and Br2 When 1 equivalent of the halogen is used,
Read moreOxidation of Alkynes with Ozone and KMnO4 As we’ve seen previously, alkenes (olefins) can be oxidized to carbonyl compounds (aldehydes, ketones, carboxylic acids) with ozone
Read moreBromination, Chlorination, and Halohydrin Formation from Alkenes Alkenes undergo halogenation when treated with Cl2, Br2 and (less commonly) I2 to give vicinal dihalides These reactions
Read moreHydrates, Hemiacetals, and Acetals – Their Formation From Aldehydes/Ketones, And Mechanisms That Are As Easy As P-A-D-P-E-A-D Hydrates, hemiacetals and acetals are the products of
Read moreAmide Hydrolysis – Conversion of Amides To Carboxylic Acids In this post we discuss examples and mechanism of acidic hydrolysis of amides, as well as
Read moreOne of the joys of this video is watching the reactions of the audience as it is revealed that song after familar song – from
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