The Second-Most Important Mechanism In Carbonyl Chemistry – Carbonyl Elimination The reverse of nucleophilic addition to the C=O bond (giving a tetrahedral intermediate) is elimination
Read moreProton Transfer All acid-base reactions are technically proton transfers, where a bond to H+ breaks, and a bond to H+ forms. However, the term “proton
Read moreThe Simple Two-Step Pattern For Seven Key Reactions Of Aldehydes And Ketones “There are just so many reactions! I can’t remember all the mechanisms!!” – distressed
Read moreToday I’m delighted to announce a new book – Practice Organic Mechanisms, co-written with Dr. Michelle Sulikowski, Senior Lecturer of Organic Chemistry at Vanderbilt University. Practice Organic
Read moreHalogenation of Alkynes With Cl2, Br2, and I2 Like alkenes, alkynes can undergo halogenation with Cl2, Br2, or I2. When 1 equivalent of the halogen
Read moreAlkyne Reaction Mechanisms That Pass Through A “Concerted” Pathway – Cyclopropanation, Hydrogenation, Hydroboration Various reactions that proceed through a concerted mechanism such as hydrogenation, hydroboration,
Read moreBromination, Chlorination, and Halohydrin Formation from Alkenes Alkenes undergo halogenation when treated with Cl2, Br2 and (less commonly) I2 to give vicinal dihalides These reactions
Read moreHow Do The Electrons Move? “Electron Pushing” With The Three Types Of Curved Arrows When learning any new reaction, I think you always have to
Read moreCurved Arrows In Organic Chemistry: Always Change Two (And Only Two!) Charges Here’s a handy little trick for accounting for charges when you draw curved
Read moreHydrates, Hemiacetals, and Acetals – Their Formation From Aldehydes/Ketones, And Mechanisms That Are As Easy As P-A-D-P-E-A-D Hydrates, hemiacetals and acetals are the products of
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