Carbocation Rearrangement Reactions (2) – Alkyl Shifts
Alkyl Shifts In Carbocation Rearrangement Reactions, Including Ring Expansion Hydride shifts can sometimes occur when a more stable carbocation can be formed through migration of
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Nucleophilic Substitution Reactions – Introduction
Introduction to Nucleophilic Substitution Reactions Today starts a new series of posts on walking through one of the key classes of reaction in organic chemistry:
Read moreTwo Types of Nucleophilic Substitution Reactions
Comparing Two Nucleophilic Substitution Reactions That Clearly Have Different Mechanisms Experiments tell us that nucleophilic substitution reactions generally fall into two main groups: In one group: The reaction
Read moreThe SN1 Mechanism
The SN1 Reaction Mechanism There are two important classes of nucleophilic substitution mechanisms – the SN1 and SN2 mechanisms (See article – Two Types of
Read moreThe Conjugate Acid Is A Better Leaving Group
Adding Acid Increases Leaving Group Ability Sure, it’s one thing to recognize halogens (Cl, Br, and I) as having high leaving group ability, as well
Read moreComparing the SN1 and SN2 Reactions
Comparing the SN1 and SN2 Reactions In nucleophilic substitution reactions, a bond between carbon and a leaving group (C–LG) is broken, and a new bond
Read moreWhat Makes A Good Leaving Group?
Good Leaving Groups Are Weak Bases A leaving group (a.k.a. “nucleofuge”) is the new Lewis base that is generated in various substitution and elimination reactions when
Read moreThe SN1, E1, and Alkene Addition Reactions All Pass Through A Carbocation Intermediate
The Carbocation Intermediate That Connects The SN1, E1, And Alkene Addition Reactions Was going to include this in my last post but it was getting
Read moreSteric Hindrance is Like a Fat Goalie
Steric Hindrance In Nucleophilic Substitution Reactions Sportswriter Todd Gallagher asked a question that every hockey fan has probably asked at one point. “Could a morbidly
Read moreChemical Kinetics
Chemical kinetics is the study of reaction rates. It can be really important in figuring out the mechanisms of chemical reactions. Here are the essentials
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