Introduction to Peptide Synthesis
Peptide bonds: Forming peptides from amino acids with the use of protecting groups Today we’ll go deeper on how to synthesize the most important amides
Read moreReactions of Diazonium Salts: Sandmeyer and Related Reactions
Diazonium Salts From Amines, And Reactions Of Diazonium Salts Today let’s talk about a set of reactions of aromatic amines, that variously are catalogued under
Read moreExo vs Endo Products In The Diels Alder: How To Tell Them Apart
Today we’ll cover how to tell endo– and exo- products apart in the Diels-Alder reaction. Shortcut below. For the long-winded walkthrough with lots of examples, read more below. Table
Read moreAromatic, Non-Aromatic, or Antiaromatic? Some Practice Problems
Aromatic vs Antiaromatic vs Non Aromatic Practice Exercises Our last post in this series on aromaticity went through the 4 conditions a molecule must fulfill
Read moreHOMO and LUMO In the Diels Alder Reaction
The HOMO and LUMO In The Diels Alder Reaction The Diels-Alder reaction is a concerted reaction between a diene (with 4 pi-electrons) and a dienophile
Read moreAntiaromatic Compounds and Antiaromaticity
Antiaromatic Compounds Are Unusually Unstable What are the key factors that determine whether a molecule is antiaromatic? It is similar to the requirements for aromaticity,
Read moreWhy Are Endo vs Exo Products Favored in the Diels-Alder Reaction?
[Advanced] Secondary Orbital Interactions – A Rationale For Why Endo Products Are Favored In The Diels-Alder Reaction In our last post, we noted that endo products tend to be
Read moreEnantiomers vs Diastereomers vs The Same? Two Methods For Solving Problems
Are These Molecules Enantiomers, Diastereomers or The Same? A classic exam question is to determine whether two molecules are enantiomers, diastereomers or the same. This
Read moreThe Pi Molecular Orbitals of Benzene
The Pi Molecular Orbitals of Benzene Today, let’s go through how to draw out the molecular orbitals of benzene. We’ll compare them with the molecular
Read moreDiels-Alder Reaction: Kinetic and Thermodynamic Control
Kinetic and Thermodynamic Control In The Diels-Alder Reaction: The Diels Alder Reaction Is Reversible At High Temperatures We’ve seen that the products of addition to
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