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The Single Swap Rule

I don’t think there are that many “tricks” to doing well in organic chemistry, but there are a few. I was kind of surprised last

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Are these molecules conjugated?

If Org 2 has an overall theme, it’s “resonance”. Today’s post has a very simple message. Atoms with lone pairs, π bonds, radicals, and carbocations can

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Nucleophilicity of Amines

Bonus Topic – Nucleophilicity Of Amines The relative nucleophilicity of amines doesn’t get a  lot of coverage (translation: doesn’t get tested) in many organic chemistry

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Alkylation of Amines (Sucks!)

Why Alkylation Of Amines (aka “The Williamson Ether Synthesis, But For Amines” ) Usually Doesn’t Pan Out Trends in the basicity of amines provide a

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