Five Key Factors That Influence Acidity
Five Key Factors That Affect Acidity Today we’ll talk about five key factors that determine acidity for different molecules and a mnemonic (ARIO, or CARDIO)
Read moreFactors That Affect Base Strength In Organic Chemistry
Basicity In Organic Chemistry: Some Basicity Trends In this article we go through some important basicity trends in organic chemistry. (Previous article – Acidity Trends) The
Read moreOrganic Chemistry Study Tips: Reaction Maps
This time of year one of the most common problems students come to me with is how to do synthesis problems. Like this: There’s a
Read moreComparing the SN1 and SN2 Reactions
Comparing the SN1 and SN2 Reactions In nucleophilic substitution reactions, a bond between carbon and a leaving group (C–LG) is broken, and a new bond
Read moreAcid-Base Reactions: Introducing Ka and pKa
The Acidity Constant Ka (And Its Negative Logarithm pKa ) Is An Extremely Useful Measure Of Acidity So last time we went through all the
Read moreStructure Determination Case Study: Deer Tarsal Gland Pheromone
A Roadmap For Structure Determination of Organic Compounds Male black-tailed deer emit a pheromone from their tarsal gland that attracts female deer. Say you had
Read moreHow to Use a pKa Table
Today we’ll talk about an incredibly important skill that might take some time to grasp but pays tremendous dividends. We’ll go through the exact details of how to use a pKa table. Understanding the proper use of a pKa table will give you the ability to recognize which acid-base reactions will happen and which will not. This will come up a lot as you progress through Org 1 and Org 2. It might be helpful to go back and review some of the factors that affect acidity that were talked about earlier.
Read moreThe pKa Table Is Your Friend
The importance of pKa values in organic chemistry can’t be overestimated, in my opinion. Not knowing pKa values in organic chemistry is like not knowing
Read moreGrignard Reagents For Addition To Aldehydes and Ketones
Grignard Reagents: Their Formation, Reactions, And Reaction Mechanisms Today’s reagent is one that most students have experience in making at some point or another. Grignard
Read moreNucleophilicity vs. Basicity
Understanding The Differences Between Nucleophilicity vs Basicity Following up on Nucleophiles and Electrophiles, here’s a common question students have about nucleophilicity: 1. What’s the difference
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