Thermodynamic and Kinetic Products
Thermodynamic vs Kinetic Products In Purchasing Decisions (And Addition To Dienes) A post about getting what you pay for, and how that translates to “kinetic
Read moreThe Wolff-Kishner, Clemmensen, And Other Carbonyl Reductions
The Wolff-Kishner, Clemmensen, and Other Fun Reductions In this post we go through 4 ways of reducing C=O to CH2 including: The Wolff-Kishner reaction The
Read moreThe Gabriel Synthesis
The Gabriel Synthesis For Making Primary Amines We’ve seen previously that it’s hard to *usefully* build amines through the SN2 reaction, because once amines start
Read moreMore Reactions on the Aromatic Sidechain: Reduction of Nitro Groups and the Baeyer Villiger
Here we cover three new reactions of aromatic substituents: reduction of nitro groups to amines, protection of amines as amides, and the Baeyer-Villiger oxidation of
Read moreReducing Sugars
Reducing Sugars Reducing sugars are small carbohydrates (usually containing one or two sugar units) that are capable of acting as reducing agents towards metal salts
Read moreMore On 1,2 and 1,4 Additions To Dienes
Two More Diene Reactions: Free-Radical Addition of HBr to Dienes, and Addition of Br2 to Dienes In an earlier post we covered 1,2 and 1,4
Read moreAldehydes and Ketones: 14 Reactions With The Same Mechanism
The Simple Two-Step Pattern For Seven Key Reactions Of Aldehydes And Ketones “There are just so many reactions! I can’t remember all the mechanisms!!” – distressed
Read moreAromatic Synthesis (1) – “Order Of Operations”
Planning An Aromatic Synthesis: Putting Reactions In The Right Order When planning a synthesis of simple aromatic compounds, it’s not enough to pick the right
Read moreSome Reactions of Azides
Azide Ion: Structure, Properties, and Substitution Reactions Table of Contents The Azide Ion Is A Great Nucleophile Organic Azides As “Masked” Amines Exploding On The
Read moreSynthesis of Benzene Derivatives (2) – Polarity Reversal
Synthesis of Benzene Derivatives: Converting ortho-,para- directors into meta- directors and vice versa. In planning the synthesis of simple benzene derivatives and other aromatic compounds,
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